Research at Huntington Health

At Huntington Health we are committed to improving medical care and outcomes through research innovation. Our clinical research department provides support for medical research in a clinical setting. Carefully selected clinical research trials complement our compassionate community care and allow our physicians and nurses to explore new ideas and push the practice of medicine forward.

Our Clinical Trials

Whether we are studying a new leadless pacemaker that can reduce infection and restriction of patient mobility, or examining new methods of pain control for women undergoing breast cancer surgery, our team is always looking for new ways to improve patients’ outcomes and experiences.

For more information, contact our clinical research department at (626) 397-3877.

Currently we have many open clinical trials. Some highlights from these programs include:

  • Cardiovascular. Our cardiovascular trials include studies of investigational drugs for irregular heartbeats, congestive heart failure, pulmonary embolisms, etc. We also conduct clinical trials of approved and investigational devices.
  • Infectious Disease. Our Long COVID trials study the cause of this disease as well as its neurological effects.
  • Neurology. Our neurology studies look at drugs that may help prevent and treat strokes and TIAs (transient ischemic attacks).
  • Non-therapeutic. Our non-therapeutic studies focus on general surgery, imaging, pharmacy, emergency care, etc., which all aim to improve care for our patients.
  • Oncology. The oncology trials at our cancer center are conducted by Cedars-Sinai. Learn more here.

Innovation in Care Program

Funding preliminary research is necessary for big medical breakthroughs. If a Huntington staff member or affiliated physician has an innovative idea to help advance medical care, they are invited to apply for our Innovation in Care Program that offers seed funding to kick-off their research. We are happy to support innovative improvements in care and award this to two clinical researchers annually.

Nursing Research and Innovation

At Huntington Health we are committed to advancing nursing excellence and nursing care through nursing research. RNs learn how to find research evidence and best practices in order to improve nursing care and support care delivery. RNs participate in nursing research to systematically solve clinical problems they identify and present these findings to inform others at professional conferences. Learn more about nursing research.

For Patients

As a Huntington Health patient, you will always receive excellent medical care. You may also be eligible to gain access to research trials. Participation in research can help advance future medical treatments, and the team at Huntington values the commitment made by our patients who choose to participate in clinical trials.

Our clinical research department is staffed by professional nurses who are dedicated to clinical research and their patients. They provide exceptional care and are available to provide support and answer questions should you choose to participate in a clinical trial.

To find out if you are a good candidate for a current research trial, call us at (626) 397-3877.

For Sponsors

As an organization we value research activity. Our commitment to clinical investigation and comprehensive support will make us an excellent partner in your efforts to bring new treatments to patients. Huntington Health has been the research program of choice for many research sponsors, due to our large and complex patient population. Additionally, we provide excellent support including detailed record-keeping and a strict dedication to quality control.

Our research team is staffed by full-time registered nurses dedicated solely to our clinical trials, a full-time regulatory manager, and support staff to manage regulatory requirements, contracts and budgets. Our research nurses bring over 100 years of combined nursing experience, and over 25 years of combined research experience.

We have experience with NIH, NCI, NHLBI, NINDS, and industry sponsored studies. We work with many large research institutes, pharmaceutical companies, medical device companies, and CROs. Most of our current sponsors have worked with us for several years and on many different studies demonstrating their satisfaction in our program and their confidence in our results. We have also built ongoing relationships with industry and academic research partners. Additionally, we have investigator-initiated studies in a variety of fields.

We are working with new sponsors all of the time and would welcome the opportunity to work with you.

To learn more about how we may be able to work together, call (626) 397-3877.


Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

Standard or Comprehensive Radiation Therapy in Treating Patients with Early-Stage Breast Cancer Previously Treated with Chemotherapy and Surgery

T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy


A Trial to Evaluate Renal Artery Denervation in Addition to Catheter Ablation to Eliminate Atrial Fibrillation

EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis (EARLY TAVR)

Clinical Trial of Atrial Fibrillation Patients Comparing Left Atrial Appendage Occlusion Therapy to Non-vitamin K Antagonist Oral Anticoagulants


PEERLESS II: RCT of FlowTriever vs. Anticoagulation Alone in Pulmonary Embolism

Infectious Disease

Evaluating the Response of the Immune System of People With Long COVID (LCRC) (enrollment by invitation)


Statins In Intracerebral Hemorrhage (SATURN)

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery (ASPIRE)

Embolization of the Middle Meningeal Artery With ONYX™ Liquid Embolic System for Subacute and Chronic Subdural Hematoma (EMBOLISE)

Study Indications.

  • Atrial fibrillation.
  • Aortic valve stenosis.
  • Breast Cancer
  • Ischemic stroke.
  • Long Covid – immune response
  • Long Covid – neurologic effects
  • Hemorrhagic stroke.
  • Melanoma
  • Post-vaccine (SARS CoV2) antibody response
  • Pulmonary embolism
  • Stroke of unknown origin.