Cancer Clinical Trials

Thanks to our affiliation with Cedars-Sinai, our cancer center is able to offer local patients access to certain clinical trials. When you participate in a clinical trial, you can play a more active role in your own health care, gain access to new research treatments before they are widely available, and help us develop new medical treatments and cures for diseases.

Through the power of clinical trials, our researchers discover new opportunities for advancement in cancer research. Whether testing a drug, device, vaccine or other therapy, our goal remains the same. We want to find better ways to treat people with cancer.

The below cancer clinical trials are currently available, close to home. Ask your doctor if you qualify to help advance your own cancer care and the care of future cancer patients by participating in a clinical trial.

Clinical Trials Open at Huntington Cancer Center

• A011801 – T-DM1 and Placebo Compared With T-DM1 AND Tucatinib in HER2-Positive Breast Cancer; Co-Investigator: Tina Wang, M.D. link to study
• A012103 – OptimICE-PCR: De-Escalation of Therapy in Early-Stage TNBC Patients Who Achieve pCR After Neoadjuvant Chemotherapy with Checkpoint Inhibitor Therapy; Co-Investigator Tina Wang, M.D. 
  link to study
• IIT2023 -09-Chung-UpfrontTAD – Upfront TAD/SNB in T1-2N0 ER+ Her2- Breast Cancer With Ultrasound-Detected Nodal Metastases; Co-Investigator: Jeannie Shen, M.D. link to study
• NRG-BR007 – A Phase III Clinical Trial Evaluating Deescalation Of Breast Radiation For Conservative Treatment Of Stage I, Hormone Sensitive, Her2-Negative, Oncotype Recurrence Score <-18 Breast Cancer (DEBRA*) (*DE-escalation of Breast RAdiation) Co-Investigators: Jeannie Shen, M.D. and Marc Botnick, M.D. link to study
• NRG-BR009 – A Phase III Adjuvant Trial Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression plus Endocrine Therapy in Pre-menopausal Patients (OFSET); Co-investigator: Niki Tank, M.D. link to study
• NRG-CC008 – A Non-Randomized Prospective Clinical Trial Comparing the Non-Inferirority of Salpingectomy to Salpingo-Oophorectomy to Reduce the Risk of Ovarian Cancer Among BRCA1 Carriers [SOROCk]; Co-Investigator Paul Lin, M.D. link to study
• S2015 – Melanoma Margins Trial (MelMarT) A Phase III, Multi-Centre, Multi-National Randomised Control Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma; Co-Investigator Alicia Terando, M.D. link to study
• S2212 – Shorter Anthracycline-Free Chemo Immunotherapy Adapted to Pathological Response in Early Triple Negative Breast Cancer (SCARLET), A Randomized Phase III Study: Co-Investigator Tina Wang, M.D. link to study